TY - JOUR
T1 - Effect of eight common Brazilian drugs on Lemna minor and Salvinia auriculata growth
AU - Otomo, Juliana Ikebe
AU - Araujo de Jesus, Tatiane
AU - Coelho, Lucia Helena Gomes
AU - Monteiro, Lucilena Rebelo
AU - Hunter, Colin
AU - Helwig, Karin
AU - Roberts, Joanne
AU - Pahl, Ole
N1 - Acceptance from webpage
AAM: 12m embargo
PY - 2021/4/10
Y1 - 2021/4/10
N2 - The growth of two species of macrophytes (Lemna minor and Salvinia auriculata) under the effect of a mixture of amoxicillin, caffeine, carbamazepine, dipyrone, ibuprofen, losartan, omeprazole, and tenivastatin was investigated by bioassay. Three concentration levels were utilized in this study (10, 200, and 500 μg L−1) using a growth inhibition test based on the OECD 221/2006 guidelines. The frond number, total area, and chlorophyll a level were selected as suitable end points. For L. minor, at all concentrations, a significant difference in the total frond number was observed and the growth inhibition varied from 30 to 70% at the low and high concentrations, respectively. No significant growth change was observed to S. auriculata exposed to the mixture of drugs. Thus, individual drug tests were performed for L. minor which demonstrated stimulation in growth, when exposed to most drugs individually, except tenivastatin which was identified as the drug responsible for the significant growth inhibition seen in the mixture. The L. minor enhanced growth was probably caused by N molecule transformation to ammonium and nitrate, essential nutrients for plants.
AB - The growth of two species of macrophytes (Lemna minor and Salvinia auriculata) under the effect of a mixture of amoxicillin, caffeine, carbamazepine, dipyrone, ibuprofen, losartan, omeprazole, and tenivastatin was investigated by bioassay. Three concentration levels were utilized in this study (10, 200, and 500 μg L−1) using a growth inhibition test based on the OECD 221/2006 guidelines. The frond number, total area, and chlorophyll a level were selected as suitable end points. For L. minor, at all concentrations, a significant difference in the total frond number was observed and the growth inhibition varied from 30 to 70% at the low and high concentrations, respectively. No significant growth change was observed to S. auriculata exposed to the mixture of drugs. Thus, individual drug tests were performed for L. minor which demonstrated stimulation in growth, when exposed to most drugs individually, except tenivastatin which was identified as the drug responsible for the significant growth inhibition seen in the mixture. The L. minor enhanced growth was probably caused by N molecule transformation to ammonium and nitrate, essential nutrients for plants.
KW - bioassay
KW - emerging contaminants
KW - macrophytes
KW - pharmaceuticals
KW - growth inhibition
U2 - 10.1007/s11356-021-13795-9
DO - 10.1007/s11356-021-13795-9
M3 - Article
JO - Environmental Science and Pollution Research
JF - Environmental Science and Pollution Research
SN - 0944-1344
ER -