Drugs-related death soon after hospital discharge among drug treatment clients in Scotland: record linkage, validation and investigation of risk factors.

Simon R. White, Sharon Hutchinson, Sheila M Bird, Elizabeth L.C. Merrall

Research output: Contribution to journalArticle

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Abstract

We validate that the 28 days after hospital-discharge are high-risk for drugs-related death (DRD) among drug users in Scotland and investigate key risk-factors for DRDs soon after hospital-discharge. Using data from an anonymous linkage of hospitalisation and death records to the Scottish Drugs Misuse Database (SDMD), including over 98,000 individuals registered for drug treatment during 1 April 1996 to 31 March 2010 with 705,538 person-years, 173,107 hospital-stays, and 2,523 DRDs. Time-at-risk of DRD was categorised as: during hospitalization, within 28 days, 29–90 days, 91 days–1 year, >1 year since most recent hospital discharge versus ‘never admitted’. Factors of interest were: having ever injected, misuse of alcohol, length of hospital-stay (0–1 versus 2+ days), and main discharge-diagnosis. We confirm SDMD clients’ high DRD-rate soon after hospital-discharge in 2006–2010. DRD-rate in the 28 days after hospital-discharge did not vary by length of hospital-stay but was significantly higher for clients who had ever-injected versus otherwise. Three leading discharge-diagnoses accounted for only 150/290 DRDs in the 28 days after hospital-discharge, but ever-injectors for 222/290. Hospital-discharge remains a period of increased DRD-vulnerability in 2006–2010, as in 1996–2006, especially for those with a history of injecting.
Original languageEnglish
Article numbere0141073
Number of pages12
JournalPLoS ONE
Volume10
Issue number11
DOIs
Publication statusPublished - 5 Nov 2015

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Drug therapy
Scotland
drug therapy
risk factors
death
drugs
Length of Stay
Pharmaceutical Preparations
Pharmaceutical Databases
Therapeutics
Hospitalization
Death Certificates
Mortality
Information Storage and Retrieval
Drug Users
injectors
Alcohols
alcohols

Keywords

  • drug users
  • death rates
  • Scotland
  • behavioral discorders
  • drug therapy
  • poisoning

Cite this

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title = "Drugs-related death soon after hospital discharge among drug treatment clients in Scotland: record linkage, validation and investigation of risk factors.",
abstract = "We validate that the 28 days after hospital-discharge are high-risk for drugs-related death (DRD) among drug users in Scotland and investigate key risk-factors for DRDs soon after hospital-discharge. Using data from an anonymous linkage of hospitalisation and death records to the Scottish Drugs Misuse Database (SDMD), including over 98,000 individuals registered for drug treatment during 1 April 1996 to 31 March 2010 with 705,538 person-years, 173,107 hospital-stays, and 2,523 DRDs. Time-at-risk of DRD was categorised as: during hospitalization, within 28 days, 29–90 days, 91 days–1 year, >1 year since most recent hospital discharge versus ‘never admitted’. Factors of interest were: having ever injected, misuse of alcohol, length of hospital-stay (0–1 versus 2+ days), and main discharge-diagnosis. We confirm SDMD clients’ high DRD-rate soon after hospital-discharge in 2006–2010. DRD-rate in the 28 days after hospital-discharge did not vary by length of hospital-stay but was significantly higher for clients who had ever-injected versus otherwise. Three leading discharge-diagnoses accounted for only 150/290 DRDs in the 28 days after hospital-discharge, but ever-injectors for 222/290. Hospital-discharge remains a period of increased DRD-vulnerability in 2006–2010, as in 1996–2006, especially for those with a history of injecting.",
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Drugs-related death soon after hospital discharge among drug treatment clients in Scotland : record linkage, validation and investigation of risk factors. / White, Simon R.; Hutchinson, Sharon; Bird, Sheila M; Merrall, Elizabeth L.C.

In: PLoS ONE , Vol. 10, No. 11, e0141073, 05.11.2015.

Research output: Contribution to journalArticle

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AU - Hutchinson, Sharon

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