Dressings and topical agents for arterial leg ulcers.

E Andrea Nelson, Matthew D Bradley

Research output: Contribution to journalArticlepeer-review

65 Citations (Scopus)


It is estimated that people in industrialised countries have a 1% chance of suffering from a leg ulcer at some time in their life. The majority of leg ulcers are associated with circulation problems; poor blood return in the veins causes venous ulcers (around 70% of ulcers) and poor blood supply to the legs causes arterial ulcers (around 25% of ulcers). Treatment of arterial leg ulcers is directed towards correcting the poor arterial blood supply, for example, by surgically correcting arterial blockages, and by supporting ulcer healing using topical agents (medicines in cream/ointment) and wound dressings. There are a large number of topical agents and wound dressings available and it is unclear what impact these have on ulcer healing.
Original languageEnglish
Article numberCD001836
Number of pages26
JournalCochrane Database of Systematic Reviews
Issue number1
Publication statusPublished - Jan 2007


  • leg ulcers
  • circulation
  • wound dressings
  • topical agents


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