Does a real-life cognitively enriched walking program “Take a Walk With Your Brain” benefit cognitive functioning and physical activity in community-dwelling older adults? A randomized controlled trial

Pauline Hotterbeex, Greet Cardon, Melanie Beeckman, Julie Latomme, Wim Fias, Stef van Puyenbroeck, Sebastien Chastin, Jannique van Uffelen*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Background and Objectives: Most studies examining combined cognitive and physical activity are conducted in laboratory settings. This randomized controlled trial (RCT) examines the effects of a real-life cognitively enriched walking program on cognitive functioning and moderate-to-vigorous physical activity (MVPA) in adults aged ≥65 years. Research Design and Methods: A three-arm RCT was conducted, comparing the cognitively enriched walking program (WALK+, doing cognitive tasks while walking) with a walking program without enrichment (WALK-only) and a passive control condition (CONT). Both WALK+ and WALK-only had a duration of 6 months, with 2 outdoors, supervised group-based sessions per week (60–90 min/session). Cognitive functioning (short- and long-term memory, executive functioning, and processing speed) and MVPA were measured at baseline, 3, 6, and 12 months using the Cambridge Neuropsychological Test Automated Battery (CANTAB) and ActiGraph GT3X+ accelerometers, respectively. Results: A total of 148 community-dwelling adults (median age: 69 years, range: 65–85; 72% [n = 107] female) were included. Comparing WALK+ to WALK-only and CONT, and WALK-only to CONT, there were no significant intervention effects on cognitive functioning at 3, 6, or 12 months. MVPA decreased with 13 min/day in WALK+ between baseline and 12 months, while it increased between baseline and 6 months with 12 min/day in WALK-only and between 3 and 6 months with 16 min/day in CONT. Discussion and Implications: The WALK+ program did not lead to statistically significant benefits for cognitive functioning or MVPA compared to WALK-only or CONT. Future studies should explore for whom combined interventions may work and determine the optimal dosage.

Original languageEnglish
Article numbergnaf043
Number of pages15
JournalGerontologist
Volume65
Issue number6
Early online date3 Feb 2025
DOIs
Publication statusPublished - Jun 2025

Keywords

  • Combined cognitive and physical activity
  • Efficacy study
  • Intervention

ASJC Scopus subject areas

  • General Medicine

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