Detection and characterisation of visual field defects using Saccadic Vector Optokinetic Perimetry in children with brain tumours

Ian C. Murray, Conrad Schmoll, Antonios Perperidis, Harry M. Brash, Alice McTrusty, Lorraine A. Cameron, Alastair G. Wilkinson, Alan O. Mulvihill, Brian W. Fleck, Robert A. Minns

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Abstract

Purpose
To determine the ability of Saccadic Vector Optokinetic Perimetry (SVOP) to detect and characterise visual field defects in children with brain tumours using eye-tracking technology, as current techniques for assessment of visual fields in young children can be subjective and lack useful detail.

Methods
Case-series study of children receiving treatment and follow-up for brain tumours at the Royal Hospital for Sick Children in Edinburgh from April 2008 to August 2013. Patients underwent SVOP testing and the results were compared with clinically expected visual field patterns determined by a consensus panel after review of clinical findings, neuroimaging, and where possible other forms of visual field assessment.

Results
Sixteen patients participated in this study (mean age of 7.2 years; range 2.9–15 years; 7 male, 9 female). Twelve children (75%) successfully performed SVOP testing. SVOP had a sensitivity of 100% and a specificity of 50% (positive predictive value of 80% and negative predictive value of 100%). In the true positive and true negative SVOP results, the characteristics of the SVOP plots showed agreement with the expected visual field. Six patients were able to perform both SVOP and Goldmann perimetry, these demonstrated similar visual fields in every case.

Conclusion
SVOP is a highly sensitive test that may prove to be extremely useful for assessing the visual field in young children with brain tumours, as it is able to characterise the central 30° of visual field in greater detail than previously possible with older techniques.
Original languageEnglish
Pages (from-to)1563-1573
Number of pages11
JournalEye
Volume32
Issue number10
DOIs
Publication statusPublished - Oct 2018

Keywords

  • Adolescent
  • Brain Neoplasms/complications
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Male
  • Saccades/physiology
  • Sensitivity and Specificity
  • Vision Disorders/diagnosis
  • Visual Field Tests/instrumentation
  • Visual Fields/physiology

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