Delayed detection of atrial fibrillation after ischemic stroke

Hooman Kamel, Kennedy Lees, Patrick D. Lyden, Philip A. Teal, Ashfaq Shuaib, Myzoon Ali, S. Claiborne Johnston

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Detection of atrial fibrillation (AF) after ischemic stroke is important because anticoagulation is indicated to reduce the risk of recurrent stroke. However, no consensus exists about the optimum method for detecting underlying paroxysmal AF not apparent on presentation with stroke. The aim of this study was to characterize the rate, timing, and predictors of delayed detection of AF after stroke. The Virtual International Stroke Trials Archive provided data from 3464 patients in the placebo arms of 4 clinical trials of therapies for acute ischemic stroke. Patients who had AF by history or on the baseline electrocardiogram were excluded. Electrocardiograms were obtained routinely and as clinically indicated. The time to detection of AF was evaluated using Kaplan-Meier survival statistics. Cox proportional hazards analysis was used to evaluate risk factors for AF.

    Original languageEnglish
    Pages (from-to)453-457
    Number of pages5
    JournalJournal of Stroke and Cerebrovascular Diseases
    Volume18
    Issue number6
    DOIs
    Publication statusPublished - Nov 2009

    Keywords

    • stroke
    • ischemic stroke
    • atrial fibrillation
    • cerebrovascular disease

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