Delayed detection of atrial fibrillation after ischemic stroke

Hooman  Kamel; Kennedy   Lees; Patrick D.  Lyden; Philip A.  Teal; Ashfaq  Shuaib; Myzoon Ali; S. Claiborne                                 Johnston

doi:10.1016/j.jstrokecerebrovasdis.2009.01.012

Delayed detection of atrial fibrillation after ischemic stroke

Hooman Kamel, Kennedy Lees, Patrick D. Lyden, Philip A. Teal, Ashfaq Shuaib, Myzoon Ali, S. Claiborne Johnston

Research output: Contribution to journal › Article

Abstract

Detection of atrial fibrillation (AF) after ischemic stroke is important because anticoagulation is indicated to reduce the risk of recurrent stroke. However, no consensus exists about the optimum method for detecting underlying paroxysmal AF not apparent on presentation with stroke. The aim of this study was to characterize the rate, timing, and predictors of delayed detection of AF after stroke. The Virtual International Stroke Trials Archive provided data from 3464 patients in the placebo arms of 4 clinical trials of therapies for acute ischemic stroke. Patients who had AF by history or on the baseline electrocardiogram were excluded. Electrocardiograms were obtained routinely and as clinically indicated. The time to detection of AF was evaluated using Kaplan-Meier survival statistics. Cox proportional hazards analysis was used to evaluate risk factors for AF.

Original language	English
Pages (from-to)	453-457
Number of pages	5
Journal	Journal of Stroke and Cerebrovascular Diseases
Volume	18
Issue number	6
DOIs	https://doi.org/10.1016/j.jstrokecerebrovasdis.2009.01.012
Publication status	Published - Nov 2009

Keywords

stroke
ischemic stroke
atrial fibrillation
cerebrovascular disease

Documents and Links

10.1016/j.jstrokecerebrovasdis.2009.01.012

http://www.strokejournal.org/article/S1052-3057(09)00031-7/abstract

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Kamel, H., Lees, K., Lyden, P. D., Teal, P. A., Shuaib, A., Ali, M., & Johnston, S. C. (2009). Delayed detection of atrial fibrillation after ischemic stroke. Journal of Stroke and Cerebrovascular Diseases, 18(6), 453-457. https://doi.org/10.1016/j.jstrokecerebrovasdis.2009.01.012

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abstract = "Detection of atrial fibrillation (AF) after ischemic stroke is important because anticoagulation is indicated to reduce the risk of recurrent stroke. However, no consensus exists about the optimum method for detecting underlying paroxysmal AF not apparent on presentation with stroke. The aim of this study was to characterize the rate, timing, and predictors of delayed detection of AF after stroke. The Virtual International Stroke Trials Archive provided data from 3464 patients in the placebo arms of 4 clinical trials of therapies for acute ischemic stroke. Patients who had AF by history or on the baseline electrocardiogram were excluded. Electrocardiograms were obtained routinely and as clinically indicated. The time to detection of AF was evaluated using Kaplan-Meier survival statistics. Cox proportional hazards analysis was used to evaluate risk factors for AF. ",

keywords = "stroke, ischemic stroke , atrial fibrillation, cerebrovascular disease",

author = "Hooman Kamel and Kennedy Lees and Lyden, {Patrick D.} and Teal, {Philip A.} and Ashfaq Shuaib and Myzoon Ali and Johnston, {S. Claiborne}",

year = "2009",

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doi = "10.1016/j.jstrokecerebrovasdis.2009.01.012",

language = "English",

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T1 - Delayed detection of atrial fibrillation after ischemic stroke

AU - Kamel, Hooman

AU - Lees, Kennedy

AU - Lyden, Patrick D.

AU - Teal, Philip A.

AU - Shuaib, Ashfaq

AU - Ali, Myzoon

AU - Johnston, S. Claiborne

PY - 2009/11

Y1 - 2009/11

N2 - Detection of atrial fibrillation (AF) after ischemic stroke is important because anticoagulation is indicated to reduce the risk of recurrent stroke. However, no consensus exists about the optimum method for detecting underlying paroxysmal AF not apparent on presentation with stroke. The aim of this study was to characterize the rate, timing, and predictors of delayed detection of AF after stroke. The Virtual International Stroke Trials Archive provided data from 3464 patients in the placebo arms of 4 clinical trials of therapies for acute ischemic stroke. Patients who had AF by history or on the baseline electrocardiogram were excluded. Electrocardiograms were obtained routinely and as clinically indicated. The time to detection of AF was evaluated using Kaplan-Meier survival statistics. Cox proportional hazards analysis was used to evaluate risk factors for AF.

AB - Detection of atrial fibrillation (AF) after ischemic stroke is important because anticoagulation is indicated to reduce the risk of recurrent stroke. However, no consensus exists about the optimum method for detecting underlying paroxysmal AF not apparent on presentation with stroke. The aim of this study was to characterize the rate, timing, and predictors of delayed detection of AF after stroke. The Virtual International Stroke Trials Archive provided data from 3464 patients in the placebo arms of 4 clinical trials of therapies for acute ischemic stroke. Patients who had AF by history or on the baseline electrocardiogram were excluded. Electrocardiograms were obtained routinely and as clinically indicated. The time to detection of AF was evaluated using Kaplan-Meier survival statistics. Cox proportional hazards analysis was used to evaluate risk factors for AF.

KW - stroke

KW - ischemic stroke

KW - atrial fibrillation

KW - cerebrovascular disease

U2 - 10.1016/j.jstrokecerebrovasdis.2009.01.012

DO - 10.1016/j.jstrokecerebrovasdis.2009.01.012

M3 - Article

VL - 18

SP - 453

EP - 457

JO - Journal of Stroke and Cerebrovascular Diseases

JF - Journal of Stroke and Cerebrovascular Diseases

SN - 1052-3057

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ER -