Cell-to-cell communication triggered by connexin channels plays a central role in maintaining epidermal homeostasis. Here, we discuss the role of the beta connexin subgroup, where site-specific mutations in at least 4 of these proteins lead to distinctive non-inflammatory and inflammatory hyperproliferative epidermal disorders.
- gap junction
Martin, P. E. M., & van Steensel, M. (2015). Connexins and skin disease: insights into the role of beta connexins in skin homeostasis. Cell and Tissue Research, 360(3), 645-658. https://doi.org/10.1007/s00441-014-2094-3