Abstract
Nonhealing cutaneous wounds, a major cause of morbidity and mortality, are difficult to treat. Recent studies suggest that significant increases in skin wound-healing rates occur by altering gap junction intercellular communication (GJIC). As migration of keratinocytes and fibroblasts is an important feature of wound healing, this study investigated whether migration rates in cultured normal human epidermal keratinocytes and dermal fibroblasts could be altered by modulating GJIC via connexin mimetic peptides.
Original language | English |
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Pages (from-to) | 240-249 |
Number of pages | 10 |
Journal | Wound Repair and Regeneration |
Volume | 17 |
Issue number | 2 |
DOIs | |
Publication status | Published - 1 Apr 2009 |
Keywords
- connexins
- wound healing