Comparison of human tear film osmolarity measured by electrical impedance and freezing point depression techniques

Alan Tomlinson, Louise C. McCann, Edward Pearce

Research output: Contribution to journalArticle

Abstract

Tear hyperosmolarity is diagnostic of dry eye disease (DED), yet difficulty in measurement has limited its utility; development of new instruments could facilitate its clinical application. This study compares the new OcuSense TearLab osmometer (OcuSense, Inc, San Diego, CA), based on electrical impedance “lab-on-a-chip” nanoliter technology, with the freezing point depression Clifton Osmometer (Clifton Technical Physics, Hartford, NY).

Original languageEnglish
Pages (from-to)1036-1041
Number of pages6
JournalCornea
Volume29
Issue number9
DOIs
Publication statusPublished - Sep 2010

Keywords

  • tear film
  • opthalmology
  • vision sciences

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