Comparison of human tear film osmolarity measured by electrical impedance and freezing point depression techniques

Alan Tomlinson; Louise C. McCann; Edward Pearce

doi:10.1097/ICO.0b013e3181cd9a1d

Comparison of human tear film osmolarity measured by electrical impedance and freezing point depression techniques

Alan Tomlinson, Louise C. McCann, Edward Pearce

Vision Sciences

Research output: Contribution to journal › Article › peer-review

114 Citations (Scopus)

Abstract

Tear hyperosmolarity is diagnostic of dry eye disease (DED), yet difficulty in measurement has limited its utility; development of new instruments could facilitate its clinical application. This study compares the new OcuSense TearLab osmometer (OcuSense, Inc, San Diego, CA), based on electrical impedance “lab-on-a-chip” nanoliter technology, with the freezing point depression Clifton Osmometer (Clifton Technical Physics, Hartford, NY).

Original language	English
Pages (from-to)	1036-1041
Number of pages	6
Journal	Cornea
Volume	29
Issue number	9
DOIs	https://doi.org/10.1097/ICO.0b013e3181cd9a1d
Publication status	Published - Sept 2010

Keywords

tear film
opthalmology
vision sciences

Documents and Links

10.1097/ICO.0b013e3181cd9a1d

Cite this

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title = "Comparison of human tear film osmolarity measured by electrical impedance and freezing point depression techniques",

abstract = "Tear hyperosmolarity is diagnostic of dry eye disease (DED), yet difficulty in measurement has limited its utility; development of new instruments could facilitate its clinical application. This study compares the new OcuSense TearLab osmometer (OcuSense, Inc, San Diego, CA), based on electrical impedance “lab-on-a-chip” nanoliter technology, with the freezing point depression Clifton Osmometer (Clifton Technical Physics, Hartford, NY).",

keywords = "tear film, opthalmology, vision sciences",

author = "Alan Tomlinson and McCann, {Louise C.} and Edward Pearce",

note = "<p>Originally published in: Cornea (2010), 29 (9), pp.1036-1041.</p>",

year = "2010",

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doi = "10.1097/ICO.0b013e3181cd9a1d",

language = "English",

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journal = "Cornea",

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T1 - Comparison of human tear film osmolarity measured by electrical impedance and freezing point depression techniques

AU - Tomlinson, Alan

AU - McCann, Louise C.

AU - Pearce, Edward

N1 - <p>Originally published in: Cornea (2010), 29 (9), pp.1036-1041.</p>

PY - 2010/9

Y1 - 2010/9

N2 - Tear hyperosmolarity is diagnostic of dry eye disease (DED), yet difficulty in measurement has limited its utility; development of new instruments could facilitate its clinical application. This study compares the new OcuSense TearLab osmometer (OcuSense, Inc, San Diego, CA), based on electrical impedance “lab-on-a-chip” nanoliter technology, with the freezing point depression Clifton Osmometer (Clifton Technical Physics, Hartford, NY).

AB - Tear hyperosmolarity is diagnostic of dry eye disease (DED), yet difficulty in measurement has limited its utility; development of new instruments could facilitate its clinical application. This study compares the new OcuSense TearLab osmometer (OcuSense, Inc, San Diego, CA), based on electrical impedance “lab-on-a-chip” nanoliter technology, with the freezing point depression Clifton Osmometer (Clifton Technical Physics, Hartford, NY).

KW - tear film

KW - opthalmology

KW - vision sciences

U2 - 10.1097/ICO.0b013e3181cd9a1d

DO - 10.1097/ICO.0b013e3181cd9a1d

M3 - Article

VL - 29

SP - 1036

EP - 1041

JO - Cornea

JF - Cornea

IS - 9

ER -

Comparison of human tear film osmolarity measured by electrical impedance and freezing point depression techniques

Abstract

Keywords

Documents and Links

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