Clinical effectiveness and cost-effectiveness of cholecystectomy compared with observation/conservative management for preventing recurrent symptoms and complications in adults presenting with uncomplicated symptomatic gallstones or cholecystitis: a systematic review and economic evaluation

Miriam Brazzelli*, Moira Cruickshank, Mary Kilonzo, Irfan Ahmed, Fiona Stewart, Paul McNamee, Andrew Elders, Cynthia Fraser, Alison Avenell, Craig Ramsay

*Corresponding author for this work

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