Oral administration of the standardized Ginkgo biloba extract EGb 761® has been shown to inhibit thermal hyperalgesia in rodent models of inflammatory and postsurgical pain, but the mechanism underlying these effects is not known. We sought to determine the site of action of EGb 761 by investigating the antihyperalgesic and antiinflammatory properties of EGb 761 after local and central drug administration in the rat carrageenan model of inflammation.
|Number of pages||6|
|Journal||Anesthesia and Analgesia|
|Publication status||Published - 1 May 2011|
- hermal hyperalgesia
- central drug administration
- Gingko biloba