Central and local administration of Gingko biloba extract EGb 761® inhibits thermal hyperalgesia and inflammation in the rat carrageenan model

Laura Biddlestone, Michelle Goldie, Sharron Dolan

Research output: Contribution to journalArticle

Abstract

Oral administration of the standardized Ginkgo biloba extract EGb 761® has been shown to inhibit thermal hyperalgesia in rodent models of inflammatory and postsurgical pain, but the mechanism underlying these effects is not known. We sought to determine the site of action of EGb 761 by investigating the antihyperalgesic and antiinflammatory properties of EGb 761 after local and central drug administration in the rat carrageenan model of inflammation.

Original languageEnglish
Pages (from-to)1226-1231
Number of pages6
JournalAnesthesia and Analgesia
Volume122
Issue number5
Publication statusPublished - 1 May 2011

Keywords

  • hermal hyperalgesia
  • central drug administration
  • Gingko biloba
  • pain

Fingerprint Dive into the research topics of 'Central and local administration of Gingko biloba extract EGb 761® inhibits thermal hyperalgesia and inflammation in the rat carrageenan model'. Together they form a unique fingerprint.

  • Cite this