Burden of disease of COVID-19: strengthening the collaboration for national studies

Sara Monteiro Pires*, Grant M.A. Wyper, Annelene Wengler, José L. Peñalvo, Romana Haneef, Declan Moran, Sarah Cuschieri, Hernan G. Redondo, Robby De Pauw, Scott A. McDonald, Lynelle Moon, Jad Shedrawy, Elena Pallari, Periklis Charalampous, Brecht Devleesschauwer, Elena Von Der Lippe

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

17 Citations (Scopus)
18 Downloads (Pure)


Objectives: Quantifying the combined impact of morbidity and mortality is a key enabler to assessing the impact of COVID-19 across countries and within countries relative to other diseases, regions, or demographics. Differences in methods, data sources, and definitions of mortality due to COVID-19 may hamper comparisons. We describe efforts to support countries in estimating the national-level burden of COVID-19 using disability-adjusted life years. Methods: The European Burden of Disease Network developed a consensus methodology, as well as a range of capacity-building activities to support burden of COVID-19 studies. These activities have supported 11 national studies so far, with study periods between January 2020 and December 2021. Results: National studies dealt with various data gaps and different assumptions were made to face knowledge gaps. Still, they delivered broadly comparable results that allow for interpretation of consistencies, as well as differences in the quantified direct health impact of the pandemic. Discussion: Harmonized efforts and methodologies have allowed for comparable estimates and communication of results. Future studies should evaluate the impact of interventions, and unravel the indirect health impact of the COVID-19 crisis.

Original languageEnglish
Article number907012
Number of pages8
JournalFrontiers in Public Health
Publication statusPublished - 3 Jun 2022
Externally publishedYes


  • capacity building
  • coronavirus
  • COVID-19
  • DALY
  • disability-adjusted life year
  • European Burden of Disease Network

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health


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