The study objective was to compare the clinical effectiveness and cost-effectiveness of treating upper limb spasticity due to stroke with botulinum toxin type A plus an upper limb therapy programme with the upper limb therapy programme alone. A multicentre open-label parallel-group randomised controlled trial and economic evaluation was carried out. Twelve stroke services in the north of England, UK. Participants: Three hundred and thirty-three adults with upper limb spasticity at the shoulder, elbow, wrist or hand and reduced upper limb function due to stroke more than 1 month previously.
|Journal||Health Technology Assessment|
|Publication status||Published - 1 May 2010|
- botulinum toxin
- randomized controlled trial
- upper limb
- economic analysis