Bioindicators and reproductive effects of prolonged 17ß-oestradiol exposure in a marine fish, the sand goby (Pomatoschistus minutus)

Craig D. Robinson; Elaine Brown; John A. Craft; Ian M. Davies; Colin Megginson; Colin Miller; Colin F. Moffat

doi:10.1016/j.aquatox.2006.12.020

Bioindicators and reproductive effects of prolonged 17ß-oestradiol exposure in a marine fish, the sand goby (Pomatoschistus minutus)

Craig D. Robinson, Elaine Brown, John A. Craft, Ian M. Davies, Colin Megginson, Colin Miller, Colin F. Moffat

Biological and Biomedical Sciences

Research output: Contribution to journal › Article

Abstract

The effects of 17ß-oestradiol (E2) on mortality, growth rates, sexual maturation, hepatic vitellogenin (VTG) mRNA expression and reproductive success were investigated during an 8-month, water-borne exposure of a marine fish, the sand goby (Pomatoschistus minutus). Indicators of oestrogenic exposure were investigated as predictors of population-level reproductive success. E2 exposure concentrations were (below limit of detection), 16 ± 3, 97 ± 20 and 669 ± 151 ng l-1 (bootstrap means and standard errors). The carrier solvent (ìl l-1 propan-2-ol) significantly reduced the rate of egg production compared to untreated fish, but did not significantly affect male VTG mRNA expression, brood size, or the other studied parameters.

Original language	English
Journal	Aquatic Toxicology
DOIs	https://doi.org/10.1016/j.aquatox.2006.12.020
Publication status	Published - 1 Mar 2007

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Keywords

sand goby
vitellogenin
gene expression
reproduction
marine fish

Cite this

Robinson, C. D., Brown, E., Craft, J. A., Davies, I. M., Megginson, C., Miller, C., & Moffat, C. F. (2007). Bioindicators and reproductive effects of prolonged 17ß-oestradiol exposure in a marine fish, the sand goby (Pomatoschistus minutus). Aquatic Toxicology. https://doi.org/10.1016/j.aquatox.2006.12.020

@article{6ddf61542bc641c09f90f3e26aa22ca0,

title = "Bioindicators and reproductive effects of prolonged 17{\ss}-oestradiol exposure in a marine fish, the sand goby (Pomatoschistus minutus)",

abstract = "The effects of 17{\ss}-oestradiol (E2) on mortality, growth rates, sexual maturation, hepatic vitellogenin (VTG) mRNA expression and reproductive success were investigated during an 8-month, water-borne exposure of a marine fish, the sand goby (Pomatoschistus minutus). Indicators of oestrogenic exposure were investigated as predictors of population-level reproductive success. E2 exposure concentrations were (below limit of detection), 16 ± 3, 97 ± 20 and 669 ± 151 ng l-1 (bootstrap means and standard errors). The carrier solvent ({\`i}l l-1 propan-2-ol) significantly reduced the rate of egg production compared to untreated fish, but did not significantly affect male VTG mRNA expression, brood size, or the other studied parameters.",

keywords = "sand goby, vitellogenin, gene expression, reproduction, marine fish",

author = "Robinson, {Craig D.} and Elaine Brown and Craft, {John A.} and Davies, {Ian M.} and Colin Megginson and Colin Miller and Moffat, {Colin F.}",

note = "Originally published in: Aquatic Toxicology (2007), 81 (4), pp.397-408.",

year = "2007",

month = mar

day = "1",

doi = "10.1016/j.aquatox.2006.12.020",

language = "English",

journal = "Aquatic Toxicology",

issn = "0166-445X",

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TY - JOUR

T1 - Bioindicators and reproductive effects of prolonged 17ß-oestradiol exposure in a marine fish, the sand goby (Pomatoschistus minutus)

AU - Robinson, Craig D.

AU - Brown, Elaine

AU - Craft, John A.

AU - Davies, Ian M.

AU - Megginson, Colin

AU - Miller, Colin

AU - Moffat, Colin F.

N1 - Originally published in: Aquatic Toxicology (2007), 81 (4), pp.397-408.

PY - 2007/3/1

Y1 - 2007/3/1

N2 - The effects of 17ß-oestradiol (E2) on mortality, growth rates, sexual maturation, hepatic vitellogenin (VTG) mRNA expression and reproductive success were investigated during an 8-month, water-borne exposure of a marine fish, the sand goby (Pomatoschistus minutus). Indicators of oestrogenic exposure were investigated as predictors of population-level reproductive success. E2 exposure concentrations were (below limit of detection), 16 ± 3, 97 ± 20 and 669 ± 151 ng l-1 (bootstrap means and standard errors). The carrier solvent (ìl l-1 propan-2-ol) significantly reduced the rate of egg production compared to untreated fish, but did not significantly affect male VTG mRNA expression, brood size, or the other studied parameters.

AB - The effects of 17ß-oestradiol (E2) on mortality, growth rates, sexual maturation, hepatic vitellogenin (VTG) mRNA expression and reproductive success were investigated during an 8-month, water-borne exposure of a marine fish, the sand goby (Pomatoschistus minutus). Indicators of oestrogenic exposure were investigated as predictors of population-level reproductive success. E2 exposure concentrations were (below limit of detection), 16 ± 3, 97 ± 20 and 669 ± 151 ng l-1 (bootstrap means and standard errors). The carrier solvent (ìl l-1 propan-2-ol) significantly reduced the rate of egg production compared to untreated fish, but did not significantly affect male VTG mRNA expression, brood size, or the other studied parameters.

KW - sand goby

KW - vitellogenin

KW - gene expression

KW - reproduction

KW - marine fish

U2 - 10.1016/j.aquatox.2006.12.020

DO - 10.1016/j.aquatox.2006.12.020

M3 - Article

JO - Aquatic Toxicology

JF - Aquatic Toxicology

SN - 0166-445X

ER -

Documents and Links

10.1016/j.aquatox.2006.12.020

http://researchonline.gcu.ac.uk/sls/27