Vulvovaginal candidiasis (VVC) is a global health problem affecting $75% of women at least once in their lifetime. Here we examined the epidemiology of VVC from a patient cohort to identify the causative organisms associated with VVC. Biofilm forming capacity and antifungal sensitivity profiles were also assessed. We report a shifting prevalence of Candida species with heterogeneous biofilm forming capacity, both of which are associated with altered antifungal drug sensitivity.
- candidiasis patients
Sherry, L., Kean, R., McKloud, E., O'Donnell, L. E., Metcalfe, R., Jones, B. L., & Ramage, G. (2017). Biofilms formed by isolates from recurrent vulvovaginal candidiasis patients are heterogeneous and insensitive to fluconazole. Antimicrobial Agents and Chemotherapy, 61(9). https://doi.org/10.1128/AAC.01065-17