Abstract
In this paper we report on a very sensitive biosensor based on gold asymmetric nanoantennas that are capable of enhancing the molecular resonances of C-H bonds. The nanoantennas are arranged as arrays of asymmetric-split H-shape (ASH) structures, tuned to produce plasmonic resonances with reflectance double peaks within the mid-infrared vibrational resonances of C-H bonds for the assay of deposited films of the molecule 17ß-estradiol (E2), used as an analyte. Measurements and numerical simulations of the reflectance spectra have enabled an estimated enhancement factor on the order of 105 to be obtained for a thin film of E2 on the ASH array. A high sensitivity value of 2335 nm/RIU was achieved, together with a figure of merit of approximately 8. Our experimental results were corroborated using numerical simulations for the C-H stretch vibrational resonances from the analyte, superimposed on the plasmonic resonances of the ASH nanoantennas.
Original language | English |
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Pages (from-to) | 395-406 |
Number of pages | 12 |
Journal | Biomedical Optics Express |
Volume | 8 |
Issue number | 1 |
Early online date | 21 Dec 2016 |
DOIs | |
Publication status | Published - 1 Jan 2017 |
Keywords
- biosensor
- nanoantennas
- molecular resonances