The purpose of this work is to assess the reliability of endothelial cell-density (ECD) estimates in corneas with different severity pseudoguttata.Specular microscopy was undertaken on grade 1, 2, or 3 pseudoguttata patients and age-matched controls aged 52-83 years. On high magnification prints of central cornea, areas of complete cells (all sides visible) and partial 'cells' (one or more sides obscured) were measured manually. Sets of 45 complete cells were selected, as well as 75 cells that were a mixture of complete and partial cells on guttate endothelia. ECD was calculated by a progressive averaging technique.
|Number of pages||11|
|Journal||Graefe's Archive for Clinical and Experimental Ophthalmology|
|Early online date||13 Sep 2011|
|Publication status||Published - 2012|
- vision science
- endothelial cell-density
Doughty, M., Jonuscheit, S., & Button, N. (2012). Assessment of the reliability of endothelial cell-density estimates in the presence of pseudoguttata. Graefe's Archive for Clinical and Experimental Ophthalmology, 250(1), 111-121. https://doi.org/10.1007/s00417-011-1812-8