Aspergillus fumigatus biofilms are refractory to antifungal challenge

Aspergillus fumigatus may cause infections in immunocompromised patients including patients with cystic fibrosis. A. fumigatus conidia are readily inhaled and are not cleared by the innate immune system. Respiratory infections are typified by the presence of 17th ECCMID / 25th ICC, Posters dense filamentous networks of hyphae in the pulmonary cavity and airways. These fungal mucus plugs are inherently difficult to treat, and have characteristics which resemble biofilms.