Aspergillus fumigatus biofilms are refractory to antifungal challenge

E. Mowat; J. Butcher; C. Williams; G. Ramage

Aspergillus fumigatus biofilms are refractory to antifungal challenge

E. Mowat, J. Butcher, C. Williams, G. Ramage

Biological and Biomedical Sciences

Research output: Contribution to conference › Abstract

Abstract

Aspergillus fumigatus may cause infections in immunocompromised patients including patients with cystic fibrosis. A. fumigatus conidia are readily inhaled and are not cleared by the innate immune system. Respiratory infections are typified by the presence of 17th ECCMID / 25th ICC, Posters dense filamentous networks of hyphae in the pulmonary cavity and airways. These fungal mucus plugs are inherently difficult to treat, and have characteristics which resemble biofilms.

Original language	English
Pages	S147-148
Number of pages	2
Publication status	Published - Mar 2007

Keywords

Microbiology, Mycology

Documents and Links

http://www.congrex.ch/2007/eccmid2007/

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title = "Aspergillus fumigatus biofilms are refractory to antifungal challenge",

abstract = "Aspergillus fumigatus may cause infections in immunocompromised patients including patients with cystic fibrosis. A. fumigatus conidia are readily inhaled and are not cleared by the innate immune system. Respiratory infections are typified by the presence of 17th ECCMID / 25th ICC, Posters dense filamentous networks of hyphae in the pulmonary cavity and airways. These fungal mucus plugs are inherently difficult to treat, and have characteristics which resemble biofilms.",

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AU - Mowat, E.

AU - Butcher, J.

AU - Williams, C.

AU - Ramage, G.

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N2 - Aspergillus fumigatus may cause infections in immunocompromised patients including patients with cystic fibrosis. A. fumigatus conidia are readily inhaled and are not cleared by the innate immune system. Respiratory infections are typified by the presence of 17th ECCMID / 25th ICC, Posters dense filamentous networks of hyphae in the pulmonary cavity and airways. These fungal mucus plugs are inherently difficult to treat, and have characteristics which resemble biofilms.

AB - Aspergillus fumigatus may cause infections in immunocompromised patients including patients with cystic fibrosis. A. fumigatus conidia are readily inhaled and are not cleared by the innate immune system. Respiratory infections are typified by the presence of 17th ECCMID / 25th ICC, Posters dense filamentous networks of hyphae in the pulmonary cavity and airways. These fungal mucus plugs are inherently difficult to treat, and have characteristics which resemble biofilms.

KW - Microbiology, Mycology

M3 - Abstract

SP - S147-148

ER -