Abstract
The aim of this study was to compare the properties of buccal delivery matrices (wafers) made with dextrin, ß-limit dextrin and pre-gelatinised starch. The constituent a-glucans were tested for their mucoadhesive properties in solution plus their content of crystalline material (differential scanning calorimetry, DSC). Wafers were made by lyophilisation of aqueous solutions/dispersions of the a-glucans. Physical properties of the wafers were evaluated using texture analysis, dissolution coupled to photography and scanning electron microscopy (SEM).
| Original language | English |
|---|---|
| Article number | PMID 23331905 |
| Pages (from-to) | 669-679 |
| Number of pages | 11 |
| Journal | Journal of Pharmacy and Pharmaceutical Sciences |
| Volume | 15 |
| Issue number | 5 |
| Publication status | Published - 2012 |
Keywords
- dextrin
- starch
- scanning electron microscopy
- wafers