Antimicrobial susceptibility of bacteria isolated from orthopedic implants following revision hip surgery

Michael M. Tunney, Gordon Ramage, Sheila Patrick, James R. Nixon, Philip G. Murphy, Sean P. Gorman*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

109 Citations (Scopus)

Abstract

The susceptibilities of 49 isolates recovered from orthopedic implants to seven antimicrobial agents were evaluated by the broth microdilution method. Ciprofloxacin and vancomycin were more active than gentamicin, representing aminoglycosides which are routinely incorporated into bone cement, and also more active than the preoperative antimicrobial agents cefamandole and erythromycin. The use of ciprofloxacin and vancomycin in vivo, therefore, warrants further evaluation.

Original languageEnglish
Pages (from-to)3002-3005
Number of pages4
JournalAntimicrobial Agents and Chemotherapy
Volume42
Issue number11
DOIs
Publication statusPublished - Nov 1998
Externally publishedYes

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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