Anhydrosis in the diabetic foot: a comparison of two urea creams

Stuart Baird, Christine M. Skinner, Susan Trail, Jamie S. Frankis

Research output: Contribution to journalArticlepeer-review


A study was carried out to compare the efficacy of two urea creams of different percentages in controlling anhydrosis in the diabetic foot. A total of 30 outpatients with evidence of bilateral anhydrosis participated in a double-blind incidental study. The study comprised a 6 week treatment regimen, with the application of 10% urea cream to the right foot and 25% urea cream to the left foot of participants. Analysis of results showed that both urea creams resulted in a statistically significant increase in skin hydration. However, the 25% urea cream produced a significantly greater increase in skin hydration than the 10% cream.
Original languageEnglish
Pages (from-to)122-136
Number of pages15
JournalThe Diabetic Foot Journal
Issue number3
Publication statusPublished - 2003


  • diabetic foot
  • urea creams
  • anhydrosis


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