Analyses of pig genomes provide insight into porcine demography and evolution

Research output: Contribution to journalArticle

Abstract

For 10,000 ¿years pigs and humans have shared a close and complex relationship. From domestication to modern breeding practices, humans have shaped the genomes of domestic pigs. Here we present the assembly and analysis of the genome sequence of a female domestic Duroc pig (Sus scrofa) and a comparison with the genomes of wild and domestic pigs from Europe and Asia. Wild pigs emerged in South East Asia and subsequently spread across Eurasia. Our results reveal a deep phylogenetic split between European and Asian wild boars ~1 million years ago, and a selective sweep analysis indicates selection on genes involved in RNA processing and regulation.
Original languageEnglish
Pages (from-to)393–398
Number of pages7
JournalNature
Volume491
Issue number7424
Early online date14 Nov 2012
DOIs
Publication statusPublished - Nov 2012

Keywords

  • genetics
  • porcine demography
  • porcine evolution
  • genomes

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