Abstract
Imaging biomarkers for Alzheimer’s disease include medial temporal lobe atrophy (MTLA) depicted on CT or MRI, and patterns of reduced metabolism on FDG-PET. To investigate whether MTLA on head CT predicts the diagnostic usefulness of an additional FDG-PET scan. Participants had a clinical diagnosis of Alzheimer’s disease (AD; n=37), dementia with Lewy bodies (DLB; n=30), or were similarly aged controls (n=30). We visually rated MTLA on coronally reconstructed CT scans and, separately and blind to CT ratings, abnormal appearances on FDG-PET scans.
Original language | English |
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Pages (from-to) | 491-496 |
Number of pages | 6 |
Journal | British Journal of Psychiatry |
Volume | 208 |
Issue number | 5 |
Early online date | 3 May 2016 |
DOIs | |
Publication status | Published - May 2016 |
Keywords
- Alzheimer’s disease
- imaging biomarkers
- temporal lobe atrophy