An aphasia research agenda – a consensus statement from the collaboration of aphasia trialists

Myzoon Ali*, Efstathia Soroli, Luis M.T. Jesus, Madeline Cruice, Jytte Isaksen, Evy Visch-Brink, Kleanthes K. Grohmann, C. Jagoe, Tarja Kukkonen, Spyridoula Varlokosta, Carlos Hernandez-Sacristan, Vicente Rosell-Clari, Rebecca Palmer, Sylvia Martinez-Ferreiro, Erin Godecke, Sarah J. Wallace, Ruth McMenamin, David Copland, Caterina Breitenstein, Audrey BowenAnn-Charlotte Laska, Katerina Hilari, Marian C. Brady, Collaboration of Aphasia Trialists (CATs)

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)
80 Downloads (Pure)


Coordination ofinternational aphasia research would minimise duplication of effort, supportsynergistic international activities across languages and multidisciplinaryperspectives, and promote high-quality conduct and reporting of aphasiaresearch, thereby increasing the relevance, transparency, and implementation offindings. The Collaboration of Aphasia Trialists (CATs) sought to develop anaphasia research agenda to direct future research activities, based onpriorities shared by people with aphasia, family members, and healthcareprofessionals. Our established international research network spanning 33countries contributed to this activity. Research literature reporting thepriorities of stakeholders was reviewed and synthesized (phase 1).Representatives from Working Groups on Aphasia Assessment & Outcomes,Prognosis & Predictors of Recovery, Effectiveness of Interventions, andSocietal Impact & Reintegration participated in a two-day researchagenda-setting meeting. The CATs expert panel refined research objectives andidentified constituent components of research and methodological developmentsrequired to address these research components. The objectives and researchcomponents were grouped into overarching themes (phase 2). The resultant listwas then circulated to more than 180 CATs members for review, revision, andapproval. Consensus on the final aphasia research agenda and roadmap wasreached by CATs executive committee (phase 3). The expert panel identified fiveoverarching research themes: (i) evidence-based interventions for people withaphasia, (ii) effective interventions to support those communicating withpeople with aphasia, (iii) cross-linguistic assessment and core outcomes foraphasia research, (iv) predictors of language recovery, and (v) clinicalimplementation of research findings. Within these broad themes, 30 researchobjectives and 91 individual aphasia research components were identified andsequentially ordered. This agenda builds on research priorities identified bypeople with aphasia and their families, and includes priorities of healthcareprofessionals and researchers, and will support the rehabilitation and recoveryof people with aphasia. Our internationally relevant research agenda promotesrigor in methodology, considers international applicability, synergisticactivities, and sharing of resources and expertise.

Original languageEnglish
Pages (from-to)555-574
Number of pages20
Issue number4
Early online date29 Aug 2021
Publication statusPublished - 3 Mar 2022


  • aphasia
  • research
  • consensus
  • priorities
  • agenda

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Developmental and Educational Psychology
  • Language and Linguistics
  • LPN and LVN
  • Otorhinolaryngology
  • Linguistics and Language


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