Absolute quantification of oxygenated hemoglobin within the visual cortex with infrared spectroscopy (fNIRS)

Michelle McIntosh, Uma Shahani, Richard G. Boulton, Daphne L. McCulloch

Research output: Contribution to journalArticlepeer-review

Abstract

The purpose of this research was to examine absolute changes in oxygenated (HbO) and deoxygenated (Hb) hemoglobin concentrations over the visual cortex in response to visual stimulation. Before this study, only relative changes have been reported at the visual cortex. Near infrared spectroscopy (NIRS) can be used to assess changes in hemoglobin concentration in tissue. A frequency domain oximeter with a specially designed probe was placed over the visual cortex while the participant viewed a checkerboard stimulus. The stimulus was alternated at 7.5 Hz for 30 seconds before being replaced by a control gray screen.

Original languageEnglish
Pages (from-to)4856-4860
Number of pages5
JournalInvestigative Ophthalmology and Visual Science
Volume51
Issue number9
Publication statusPublished - 1 Mar 2010

Keywords

  • haemoglobin
  • vision sciences
  • visual cortex

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