Absence of xenotropic murine leukaemia virus-related virus in UK patients with chronic fatigue syndrome

Harriet C.T. Groom, Virginie C. Boucherit, Kerry Makinson, Edward Randal, Sarah Baptista, Suzanne Hagan, John W. Gow, Frank M. Mattes

Research output: Contribution to journalArticle

Abstract

Detection of a retrovirus, xenotropic murine leukaemia virus-related virus (XMRV), has recently been reported in 67% of patients with chronic fatigue syndrome. We have studied a total of 170 samples from chronic fatigue syndrome patients from two UK cohorts and 395 controls for evidence of XMRV infection by looking either for the presence of viral nucleic acids using quantitative PCR (limit of detection copies) or for the presence of serological responses using a virus neutralisation assay.

Original languageEnglish
JournalRetrovirology
Volume7
Issue number10
DOIs
Publication statusPublished - 1 Feb 2010

Keywords

  • murine leukaemia virus
  • chronic fatigue syndrome

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    Groom, H. C. T., Boucherit, V. C., Makinson, K., Randal, E., Baptista, S., Hagan, S., Gow, J. W., & Mattes, F. M. (2010). Absence of xenotropic murine leukaemia virus-related virus in UK patients with chronic fatigue syndrome. Retrovirology, 7(10). https://doi.org/10.1186/1742-4690-7-10