A time since onset of injection model for hepatitis C spread amongst injecting drug users

Stephen Corson, David Greenhalgh, Sharon Hutchinson

Research output: Contribution to journalArticle

Abstract

Studies of hepatitis C virus (HCV) infection amongst injecting drug users (IDUs) have suggested that this population can be separated into two risk groups (naive and experienced) with different injecting risk behaviours. Understanding the differences between these two groups and how they interact could lead to a better allocation of prevention measures designed to reduce the burden of HCV in this population. In this paper we develop a deterministic, compartmental mathematical model for the spread of HCV in an IDU population that has been separated into two groups (naive and experienced) by time since onset of injection.
Original languageEnglish
Pages (from-to)935-978
Number of pages44
JournalJournal of Mathematical Biology
Volume66
Issue number4-5
Early online date28 Aug 2012
DOIs
Publication statusPublished - Mar 2013

Keywords

  • hepatitis C
  • mathematical model
  • injecting drug users
  • HCV

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