A clinical alternative method to fluorophotometry for measuring tear production in the diagnosis of dry eye

Louise C. McCann, Alan Tomlinson, Edward Pearce, Khanal Santosh, Stephen B. Kaye, Anthony C. Fisher

Research output: Contribution to journalArticle


This study aimed to determine the utility of the tear function index (Liverpool modification TFI) in assessing tear turnover rate (TTR), evaluate association of tear clearance rate (TCR) and TFI with measurements of TTR by fluorophotometry, and determine effectivity of these test measures in dry eye (DE) diagnosis. Forty-one subjects with DE and 15 control subjects participated. Tests included symptoms, fluorophotometry (by automated scanning fluorophotometry), and TCR and TFI from a prepared Liverpool modification TFI strip.

Original languageEnglish
Pages (from-to)745-750
Number of pages6
Issue number7
Publication statusPublished - 1 Jul 2010



  • dry eye
  • tear production
  • vision sciences

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