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2019

Are there better assays to evaluate the risk of transmission of porcine endogenous retroviruses (PERVs) to human cells?

Denner, J. & Scobie, L., 29 Aug 2019, In : Xenotransplantation. 26, 4, 3 p., e12510.

Research output: Contribution to journalLetter

2018
16 Downloads (Pure)

Assessment of porcine endogenous retrovirus transmission across an alginate barrier used for the encapsulation of porcine islets

Crossan, C., Mourad, N. I., Smith, K., Gianello, P. & Scobie, L., Dec 2018, In : Xenotransplantation. 25, 6, e12409.

Research output: Contribution to journalArticle

Open Access
File
Endogenous Retroviruses
Swine
Testis
Cultured Cells
alginic acid
38 Downloads (Pure)

Cellular xenotransplantation of animal cells into people: benefits and risk

Scobie, L., Galli, C., Gianello, P., Cozzi, E. & Schuurman, H-J., 30 Apr 2018, Scientific and Technical Review. OIE, Vol. 37. p. 113-122

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

Open Access
File
Heterologous Transplantation
Swine
Tissue and Organ Procurement
Safety
Animal Welfare
16 Downloads (Pure)

Examining the potential for porcine-derived islet cells to harbour viral pathogens

Crossan, C., O'Hara, Z., Mourad, N., Gianello, P. & Scobie, L., Apr 2018, In : Xenotransplantation. 25, 2, e12375.

Research output: Contribution to journalArticle

Open Access
File
Islets of Langerhans
Swine
Viruses
Newborn Animals
Hygiene
148 Downloads (Pure)
Open Access
File
Hepatitis E virus
Shellfish
shellfish
Scotland
supermarkets
97 Downloads (Pure)

Hepatitis E virus (HEV) in Scotland: evidence of recent increase in viral circulation in humans

Thom, K., Gilhooly, P., McGowan, K., Malloy, K., Jarvis, L. M., Crossan, C., Scobie, L., Blatchford, O., Smith-Palmer, A., Donnelly, M. C., Davidson, J. S., Johannessen, I., Simpson, K. J., Dalton, H. R. & Petrik, J., 22 Mar 2018, In : Eurosurveillance. 23, 12

Research output: Contribution to journalArticle

Open Access
File
Hepatitis E virus
Scotland
Seroepidemiologic Studies
Hepatitis E
Blood Donors
11 Downloads (Pure)

Is it currently possible to evaluate the risk posed by PERVs for clinical xenotransplantation?

Denner, J., Scobie, L. & Schuurman, H-J., 13 May 2018, In : Xenotransplantation. p. e12403

Research output: Contribution to journalComment/debate

Open Access
File
Heterologous Transplantation

PERVading strategies and infectious risk for clinical xenotransplantation

McGregor, C. G. A., Takeuchi, Y., Scobie, L. & Byrne, G., 18 Aug 2018, In : Xenotransplantation. 25, 4, p. e12402 3 p.

Research output: Contribution to journalComment/debate

Heterologous Transplantation

Theme issue on infections and safety – an introduction

Scobie, L. & Denner, J., 18 Aug 2018, In : Xenotransplantation. 25, 4, 15756802.

Research output: Contribution to journalComment/debate

Safety
Infection
39 Downloads (Pure)

Viral pathogens: what are they and do they matter?

Scobie, L., Crossan, C., Mourad, N. I., Galli, C., Perota, A. & Gianello, P., Jun 2018, In : Xenotransplantation.

Research output: Contribution to journalComment/debate

Open Access
File
2017
51 Downloads (Pure)

Characterization of porcine endogenous retrovirus expression in neonatal and adult pig pancreatic islets

Mourad, N. I., Crossan, C., Cruikshank, V., Scobie, L. & Gianello, P., Aug 2017, In : Xenotransplantation. 24, 4, e12311.

Research output: Contribution to journalArticle

Open Access
File
Endogenous Retroviruses
Islets of Langerhans
Swine
Pancreas
Heterologous Transplantation
42 Downloads (Pure)

Detection of viral hepatitis E in clinical liver biopsies

Prost, S., Crossan, C. L., Dalton, H. R., De Man, R. A., Kamar, N., Selves, J., Dhaliwal, C., Scobie, L. & Bellamy, C. O. C., Oct 2017, In : Histopathology. 71, 4, p. 580-590 11 p.

Research output: Contribution to journalArticle

Open Access
File
Hepatitis E
Hepatitis E virus
Biopsy
Polymerase Chain Reaction
Liver
21 Downloads (Pure)

Hepatitis E: a concise review of virology, epidemiology, clinical presentation and therapy

Donnelly, M. C., Scobie, L., Crossan, C. L., Dalton, H., Hayes, P. C. & Simpson, K. J., Jul 2017, In : Alimentary Pharmacology and Therapeutics. 46, 2, p. 126-141 16 p.

Research output: Contribution to journalArticle

Open Access
File
Hepatitis E
Virology
Epidemiology
Infection
Therapeutics
35 Downloads (Pure)

Posttransplant lymphoproliferative disorders in neuronal xenotransplanted macaques

Cavicchioli, L., Ferraresso, S., Westmoreland, S., Kaliyaperumal, S., Knight, H., Crossan, C., Scobie, L., Danesi, A., Vadori, M., Trez, D., Aron Badin, R., Hantraye, P. & Cozzi, E., Mar 2017, In : Veterinary Pathology. 54, 2

Research output: Contribution to journalArticle

Open Access
File
lymphatic diseases
Lymphoproliferative Disorders
Macaca
Lymphocryptovirus
Primates
2016
Heterologous Transplantation
Swine
Clinical Trials
Heterografts
Immunosuppressive Agents
Heterologous Transplantation
Type 1 Diabetes Mellitus
Swine
Clinical Trials
Endogenous Retroviruses

Selective CD28 antagonist blunts memory immune responses and promotes long-term control of skin inflammation in nonhuman primates

Poirier, N., Chevalier, M., Mary, C., Hervouet, J., Minault, D., Baker, P., Ville, S., Le Bas-Bernardet, S., Dilek, N., Belarif, L., Cassagnau, E., Scobie, L., Blancho, G. & Vanhove, B., 1 Jan 2016, In : Journal of Immunology. 196, 1, p. 274-283 10 p.

Research output: Contribution to journalArticle

Primates
Inflammation
T-Lymphocytes
Skin
Lymphocyte Count