POSITIF Post Stroke Intervention Trial in Fatigue (but on proposal to funder it is called Fatigue After Stroke: Testing the Feasibility of a Brief Psychological Intervention (FAST-FAB))

  • Brady, Marian (PI)
  • Mead, Gillian (CoI)
  • Cvoro, Vera (CoI)
  • Barber, Mark (CoI)
  • Gillespie, David C. (CoI)
  • Dennis, Martin (CoI)
  • Wu, Simiao (CoI)
  • Carson, Alan (CoI)
  • Macleod, Malcolm (CoI)

    Project Details

    Description

    We propose a multicentre feasibility randomised controlled trial of a manualised brief psychological intervention for post-stroke fatigue, delivered by a nurse (six face-to-face individual sessions, two weeks apart, with a ‘booster’ telephone call at 18 weeks). The intervention was developed by a multidisciplinary team including stroke survivors. The intervention is behaviourally focused and aims to improve sleep, increase physical activity and thus reduce fatigue. A psychologist has already delivered it with 12 stroke survivors with fatigue; the intervention was acceptable and improved fatigue, self-reported mood and cognition.

    There are very few stroke psychologists in the National Health Service. Thus, we will train stroke nurses to deliver the intervention. We have previously shown that manualised interventions can be successfully delivered by nurses with appropriate training, supervised by psychologists. This is in keeping with professionally led rehabilitation interventions delivered by (trained) assistants and volunteers; systematic reviews show no evidence of a difference in effect of interventions.

    Our proposal includes a multicentre feasibility trial to determine the number of eligible patients who can be identified, the willingness of participants to be randomised, the feasibility and acceptability of the intervention when delivered by appropriately trained stroke nurses, fidelity of intervention, resources actually required to deliver the intervention (including nurse time and supervision) , adherence to the intervention, response and completion rates of questionnaires, and variability of our fatigue outcome measure to inform power calculations for a main trial. Following this feasibility trial, we will then proceed to a definitive multicentre randomised controlled trial (RCT).
    StatusFinished
    Effective start/end date1/11/1730/05/20

    Funding

    • Chest Heart & Stroke Scotland: £78,323.00

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