Retinal disorders are characterized by the degeneration of photoreceptor cells in the eye, with resulting visual defects and even blindness. Common types of retinal disorder include age-related macular degeneration (AMD) and diabetic retinopathy (DR), neither of which have effective treatment. It is well known that oxidative damage and inflammation contribute to the development of retinal disorders. Natural products, particularly those associated with Chinese medicine, have been used in the treatment of AMD and DR for thousands of years in South Asia. However, the underlying functional mechanisms are not understood. The aim of this project is to identify functional components from medicinal plants, investigate their protective effects against oxidative damage and inflammation in human retinal cells and in zebrafish, and so develop new products for the treatment of retinal disorders.
|Effective start/end date||1/08/22 → 30/11/22|
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):
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