Urinary incontinence in men after formal one-to-one pelvic-floor muscle training following radical prostatectomy or transurethral resection of the prostate (MAPS): two parallel randomised controlled trials

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  • Cathryn Glazener
  • Charles Boachie
  • Brian Buckley
  • Claire Cochran
  • Grace Dorey
  • Adrian Grant
  • Suzanne Hagen
  • Mary Kilonzo
  • Alison McDonald
  • Gladys McPherson

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Original languageEnglish
Pages (from-to)328-337
Number of pages10
JournalLancet
Volume378
Issue number9788
DOIs
StatePublished - Jul 2011

Abstract

Urinary incontinence is common immediately after prostate surgery. Men are often advised to do pelvic-floor exercises, but evidence to support this is inconclusive. Our aim was to establish if formal one-to-one pelvic floor muscle training reduces incontinence. We undertook two randomised trials in men in the UK who were incontinent 6 weeks after radical prostatectomy (trial 1) or transurethral resection of the prostate (TURP; trial 2) to compare four sessions with a therapist over 3 months with standard care and lifestyle advice only. Randomisation was by remote computer allocation. Our primary endpoints, collected via postal questionnaires, were participants' reports of urinary incontinence and incremental cost per quality-adjusted life year (QALY) after 12 months. Group assignment was masked from outcome assessors, but this masking was not possible for participants or caregivers. We used intention-to-treat analyses to compare the primary outcome at 12 months. This study is registered, number ISRCTN87696430.

Keywords

  • urinary incontinence in men, prostatectomy, prostate surgery, pelvic-floor muscle training

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