Dr. John MacLachlan

John MacLachlan
Postal address:
Glasgow Caledonian University
70 Cowcaddens Road
United Kingdom

Research interests

In summary my research interests and areas of expertise (over the past 30 years) are based on the development and application of analytical chemistry to clinical/biological and environmental/forensic problems.  I have considerable experience in GC-MS, LC-MS and related chromatographic/spectrometric techniques.  The main areas are described below:

•    Trace analysis of drugs, biogenic and xenobiotic metabolites in human body fluids and pharmaceutical/drug formulations.

•    Analysis of environmental pollutants (e.g. VOCs, dust, inorganics) in the atmosphere (indoor and outdoor).

•    Pesticide residue, dioxin/PCB and assorted micro-pollutant (e.g. pharmaceuticals) analyses in environmental matrices such as water, soil and the biosphere.

Current Projects

1      noPILLS (EU, INERREG) (Pharmaceutical Input and Elimination from Local Sources).  This is the analysis of pharmaceuticals from waste water and ground waters.

2      Biomarkers in human neurological disease, with St. Georges Hospital, University of London.

3      Also collaboration with the University of Bristol (~£3K):  LC-MS analysis of morphine and metabolites in the study of alcohol related addiction studies in mice.

4      Just finished:-BATFARM (EU, INTERREG) (Best available technology farm).  This is to monitor emissions from a typical pastoral farm.

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Research areas

  1. Published

    Ethanol reversal of tolerance to the respiratory depressant effects of morphine

    Hill, R., Lyndon, A., Withey, S., Roberts, J., Kershaw, Y., MacLachlan, J., Lingford-Hughes, A., Kelly, E., Bailey, C., Hickman, M. & Henderson, G. Jan 2016 In : Neuropsychopharmacology. 41, p. 762–773 12 p.

    Research output: Contribution to journalArticle

  2. Published
  3. Published

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